Nitrimidazine in the treatment of trichomoniasis.

Nitrimidazine compared with metronidazole in the treatment of vaginal trichomoniasis.

A new substituted nitroimidazole, nitrimidazine (Naxogin), is compared with the established drug, metronidazole (Flagyl), for the treatment of vaginal trichomoniasis in a randomized double-blind trial. Nitrimidazine cured 39 (68%) out of 57 patients and showed no undesirable effects other than nausea in one patient. Metronidazole cured 51 (89%) out of 57 patients and also caused nausea in one p...

Vaginal and oral nitrimidazine in the treatment of vaginal trichomoniasis.

Treatment of trichomoniasis with a single dose of nimorazole (nitrimidazine).

Detection of the antitrichomonal drug nitrimidazine (Naxogin) in urine.

For 10 years vaginal trichomoniasis has been treated by oral chemotherapy. Some cases appear not to respond satisfactorily to the drug used, and it is important to know whether or not the patient is taking the drug, and if so, whether or not it is being absorbed from the alimentary tract. A simple method for detecting these drugs in urine may be of use in such cases. Two antitrichomonal drugs i...

Comparison of nitrimidazine and metronidazole in the treatment of trichomonal vaginitis.

Until the introduction of metronidazole, the treatment of trichomonal vaginitis presented a considerable therapeutic problem. Local treatment was commonly followed by recurrence of the condition, doubtless partly because vaginal treatment alone failed to eliminate all foci of infection. Moreover, it became apparent that trichomonal infection was also often present in the male (Watt and Jennison...